Asymmetrical deposition and modification of histone H3 variants are essential for zygote development
A low level of H3.1/2 deposition in the perinucleolar regions of male pronuclei in zygotes prevents accumulation of H3.1/2K27me3 modification which has detrimental effect on DNA replication. The pericentromeric heterochromatin of one-cell embryos forms a unique, ring-like structure around the nucleo...
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| Format: | Artigo |
| Sprache: | Inglês |
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Life Science Alliance LLC
2021-08-01
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| Schriftenreihe: | Life Science Alliance |
| Online-Zugang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101102 |
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