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Asymmetrical deposition and modification of histone H3 variants are essential for zygote development

A low level of H3.1/2 deposition in the perinucleolar regions of male pronuclei in zygotes prevents accumulation of H3.1/2K27me3 modification which has detrimental effect on DNA replication. The pericentromeric heterochromatin of one-cell embryos forms a unique, ring-like structure around the nucleo...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Machika Kawamura, Satoshi Funaya, Kenta Sugie, Masataka G Suzuki, Fugaku Aoki
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Life Science Alliance LLC 2021-08-01
Цуврал:Life Science Alliance
Онлайн хандалт:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101102
Шошгууд: Шошго нэмэх
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