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An anti-PDGFRβ aptamer for selective delivery of small therapeutic peptide to cardiac cells.

Small therapeutic peptides represent a promising field for the treatment of pathologies such as cardiac diseases. However, the lack of proper target-selective carriers hampers their translation towards a potential clinical application. Aptamers are cell-specific carriers that bind with high affinity...

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Autors principals: Alessandra Romanelli, Alessandra Affinito, Concetta Avitabile, Silvia Catuogno, Paola Ceriotti, Margherita Iaboni, Jessica Modica, Geroloma Condorelli, Daniele Catalucci
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC5841773?pdf=render
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