Targeting Insulin Receptor with a Novel Internalizing Aptamer

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...

Full beskrivning

Bibliografiska uppgifter

Huvudupphov:	Margherita Iaboni, Raffaela Fontanella, Anna Rienzo, Maria Capuozzo, Silvia Nuzzo, Gianluca Santamaria, Silvia Catuogno, Gerolama Condorelli, Vittorio de Franciscis, Carla Lucia Esposito
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2016-01-01
Serie:	Molecular Therapy: Nucleic Acids
Ämnen:	aptamer cancer therapy IGF-1R IR SELEX
Länkar:	http://www.sciencedirect.com/science/article/pii/S2162253117300914
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!