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Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis

Abstract Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung, which is associated with different lung disease. Treatment options are still sparse. Nintedanib, an oral tyrosine kinase inhibitor, significantly slows the LF progression. However, there is a str...

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Auteurs principaux: Amara Khan, M. Andrea Markus, Angelika Svetlove, Swen Hülsmann, Frauke Alves, Christian Dullin
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2023-10-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-023-45305-x
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