Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone

Mitochondrial dysfunction has been implicated in Parkinson's disease (PD) neuropathology. Mic60, also known as mitofilin, is a protein of the inner mitochondrial membrane and a key component of the mitochondrial contact site and cristae junction organizing system (MICOS). Mic60 is critical for maint...

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Autors principals:	Victor S. Van Laar, Sarah B. Berman, Teresa G. Hastings
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2016-07-01
Col·lecció:	Neurobiology of Disease
Matèries:	Mitofilin Mic60 Parkinson's disease Mitochondria Mitochondrial dynamics Fission
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0969996116300596
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