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Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications

<p>Abstract</p> <p>Background</p> <p>Metastatic renal cell carcinoma (RCC) is highly resistant to systemic chemotherapy. Unfortunately, nearly all patients die of the metastatic and chemoresistant RCC. Recent studies have shown the atypical PKCζ is an important regulator of tumorigenesis. However, t...

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Principais autores: Pu Yeong-Shiau, Huang Chao-Yuan, Chen Jyue-Yu, Kang Wang-Yi, Lin Ying-Chu, Shiu Yu-Shiang, Chuang Shu-Ju, Yu Hong-Jeng, Lai Ming-Kuen, Tsai Yu-Chieh, Wu Wen-Jeng, Hour Tzyh-Chyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-04-01
coleção:Journal of Biomedical Science
Assuntos:
Renal cell carcinoma
PKCζ
Immunohistochemistry
Chemoresistance
Cytotoxicity
Acesso em linha:http://www.jbiomedsci.com/content/19/1/39
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