Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications

<p>Abstract</p> <p>Background</p> <p>Metastatic renal cell carcinoma (RCC) is highly resistant to systemic chemotherapy. Unfortunately, nearly all patients die of the metastatic and chemoresistant RCC. Recent studies have shown the atypical PKCζ is an important regulator of tumorigenesis. However, t...

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Autori principali:	Pu Yeong-Shiau, Huang Chao-Yuan, Chen Jyue-Yu, Kang Wang-Yi, Lin Ying-Chu, Shiu Yu-Shiang, Chuang Shu-Ju, Yu Hong-Jeng, Lai Ming-Kuen, Tsai Yu-Chieh, Wu Wen-Jeng, Hour Tzyh-Chyuan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2012-04-01
Serie:	Journal of Biomedical Science
Soggetti:	Renal cell carcinoma PKCζ Immunohistochemistry Chemoresistance Cytotoxicity
Accesso online:	http://www.jbiomedsci.com/content/19/1/39
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