A SARS-CoV-2 NSP7 homolog of a Treg epitope suppresses CD4+ and CD8+ T cell memory responses

Pathogens escape host defenses by T-cell epitope mutation or deletion (immune escape) and by simulating the appearance of human T cell epitopes (immune camouflage). We identified a highly conserved, human-like T cell epitope in non-structural protein 7 (NSP7) of SARS-CoV-2, RNA-dependent RNA polymer...

Descrizione completa

Dettagli Bibliografici

Autori principali:	S. M. Shahjahan Miah, Sandra Lelias, Andres H. Gutierrez, Mitchell McAllister, Christine M. Boyle, Lenny Moise, Anne S. De Groot
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-11-01
Serie:	Frontiers in Immunology
Soggetti:	SARS-CoV-2 Tregitope nsp7 tolerance immunogenicity immune camouflage
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1290688/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!