A 7-gene expression signature predicts immune microenvironment remodeling and neoadjuvant chemo-immunotherapy response in lung squamous cell carcinoma

BackgroundNeoadjuvant chemo-immunotherapy (NCI) has significantly improved outcomes in advanced lung squamous cell carcinoma (LUSC). However, some patients remain resistant to NCI, resulting in poor outcomes. The mechanisms behind this resistance remain unclear.MethodsForty LUSC patients receiving N...

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Hlavní autoři:	Shaoling Li, Junhong Guo, Yan Huang, Zhengwei Dong, Ranyue Wang, Huifang Liu, Yaoqi Xiao, Jin Wang, Xing Li, Zhan Huang, Tao Hu, Changbin Zhu, Likun Hou, Chunyan Wu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-02-01
Edice:	Frontiers in Immunology
Témata:	HOXC13 lung squamous cell carcinoma neoadjuvant chemo-immunotherapy RNA sequencing tumor microenvironment
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1696792/full
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