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Pleural tuberculosis in patients with early HIV infection is associated with increased TNF-alpha expression and necrosis in granulomas.

Although granulomas may be an essential host response against persistent antigens, they are also associated with immunopathology. We investigated whether HIV co-infection affects histopathological appearance and cytokine profiles of pleural granulomas in patients with active pleural tuberculosis (TB...

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Autori principali: Juanita Bezuidenhout, Teri Roberts, Liesel Muller, Paul van Helden, Gerhard Walzl
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2009-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2626629?pdf=render
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