Structural and molecular basis of specialized translation mediated by the ribosome mRNA-binding channel

Abstract The ribosome mRNA channel is central to translation, yet its role in regulatory mechanisms remains unclear. Using cryo-EM of human ribosomal complexes bound to Kozak and TISU mRNAs from wild-type (WT) and RPS26/eS26 mutant (RPS26dC) cells, we demonstrate that both RPS26/eS26 and mRNA adopt...

Volledige beschrijving

Bewaard in:

Bibliografische gegevens
Hoofdauteurs:	Davide Fraticelli, Disha Gajanan Hiregange, Benjamin Weiss, Ariel Ogran, Tal Havkin-Solomon, Irene Martinez Roman, Anat Bashan, Ada Yonath, Rivka Dikstein
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Portfolio 2026-04-01
Reeks:	Nature Communications
Online toegang:	https://doi.org/10.1038/s41467-026-72263-5
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!

Structural and molecular basis of specialized translation mediated by the ribosome mRNA-binding channel

Gelijkaardige items