Structural and molecular basis of specialized translation mediated by the ribosome mRNA-binding channel
Abstract The ribosome mRNA channel is central to translation, yet its role in regulatory mechanisms remains unclear. Using cryo-EM of human ribosomal complexes bound to Kozak and TISU mRNAs from wild-type (WT) and RPS26/eS26 mutant (RPS26dC) cells, we demonstrate that both RPS26/eS26 and mRNA adopt...
Gardado en:
| Principais autores: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2026-04-01
|
| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-026-72263-5 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|