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A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus.

In human cytomegalovirus (HCMV), tropism to epithelial and endothelial cells is dependent upon a pentameric complex (PC). Given the structure of the placenta, the PC is potentially an important neutralizing antibody target antigen against congenital infection. The guinea pig is the only small animal...

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Hlavní autoři: Stewart Coleman, K Yeon Choi, Matthew Root, Alistair McGregor
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2016-07-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC4936736?pdf=render
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