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Cross Strain Protection against Cytomegalovirus Reduces DISC Vaccine Efficacy against CMV in the Guinea Pig Model

Congenital cytomegalovirus (CMV) is a leading cause of disease in newborns and a vaccine is a high priority. The guinea pig is the only small animal model for congenital CMV but requires guinea pig cytomegalovirus (GPCMV). Previously, a disabled infectious single cycle (DISC) vaccine strategy demons...

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Principais autores: K. Yeon Choi, Nadia S. El-Hamdi, Alistair McGregor
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-04-01
סדרה:Viruses
נושאים:
guinea pig
cytomegalovirus
glycoproteins
neutralizing antibody
congenital CMV
pentamer complex
גישה מקוונת:https://www.mdpi.com/1999-4915/14/4/760
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