The build-up of stock of stable integrated proviruses overtime explains the difficulty in reducing HIV-1 DNA levels when treatment is initiated at the chronic stage of the infection

Background: Understanding factors affecting the size and the evolution of the HIV reservoir is essential for the development of curative strategies. This study aimed to assess the impact of antiretroviral therapy (ART) initiated during primary infection (PHI) vs chronic infection (CHI) on the levels...

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Автори:	Gilbert Mchantaf, Antoine Cheret, Adeline Melard, Asma Essat, Elise Gardiennet, Rebecca Bauer, Caroline Charre, Vincent Meiffredy, Lionel Piroth, Cécile Goujard, Laurence Meyer, Véronique Avettand-Fenoel
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2023-12-01
Серія:	Journal of Virus Eradication
Предмети:	Integrated HIV-1 DNA Total HIV-1 DNA Early ART Deferred treatment Reservoir decay
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2055664023000432
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