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Synergistic Steatosis Induction in Mice: Exploring the Interactions and Underlying Mechanisms between PFOA and Tributyltin

This study explores the impact of environmental pollutants on nuclear receptors (CAR, PXR, PPARα, PPARγ, FXR, and LXR) and their heterodimerization partner, the Retinoid X Receptor (RXR). Such interaction may contribute to the onset of non-alcoholic fatty liver disease (NAFLD), which is initially ch...

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Principais autores: Yannick Dauwe, Lucile Mary, Fabiana Oliviero, Louise Dubois, Elodie Rousseau-Bacquie, Jelskey Gomez, Véronique Gayrard, Laïla Mselli-Lakhal
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2024-05-01
סדרה:Cells
נושאים:
nuclear receptor
PFAS
NAFLD
TBT
metabolism
synergism
גישה מקוונת:https://www.mdpi.com/2073-4409/13/11/940
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