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Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation

Constitutive androstane receptor (CAR) activation has found to ameliorate diabetes in animal models. However, no CAR agonists are available clinically. Therefore, a safe and effective CAR activator would be an alternative option. In this study, sixty courmarin derivatives either synthesized or purif...

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Principais autores: Shin-Hun Juang, Min-Tsang Hsieh, Pei-Ling Hsu, Ju-Ling Chen, Hui-Kang Liu, Fong-Pin Liang, Sheng-Chu Kuo, Chen-Yuan Chiu, Shing-Hwa Liu, Chen-Hsi Chou, Tian-Shung Wu, Hsin-Yi Hung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-12-01
coleção:Molecules
Assuntos:
Yin Chen Hao
constitutive androstane receptor
coumarin
scoparone
Acesso em linha:https://www.mdpi.com/1420-3049/26/1/164
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