Effect of antigen shedding on targeted delivery of immunotoxins in solid tumors from a mathematical model.
Most cancer-specific antigens used as targets of antibody-drug conjugates and immunotoxins are shed from the cell surface (Zhang & Pastan (2008) Clin. Cancer Res. 14: 7981-7986), although at widely varying rates and by different mechanisms (Dello Sbarba & Rovida (2002) Biol. Chem. 383: 69-83). Why m...
Na minha lista:
| Principais autores: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2014-01-01
|
| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC4208831?pdf=render |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|