Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases

Abstract Background Despite substantial research revealing that patients with rheumatoid arthritis (RA) have excessive morbidity and mortality of cardiovascular disease (CVD), the mechanism underlying this association has not been fully known. This study aims to systematically investigate the phenot...

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Autori principali:	Xiaohui Sun, Yu Qian, Weiqiu Cheng, Ding Ye, Bin Liu, Dan Zhou, Chengping Wen, Ole A. Andreassen, Yingying Mao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-04-01
Serie:	BMC Medicine
Soggetti:	Rheumatoid arthritis Cardiovascular diseases Epidemiological association Genetic correlation Pleiotropic loci
Accesso online:	https://doi.org/10.1186/s12916-024-03376-1
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