Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis

Abstract Background Irritable bowel syndrome (IBS) often co-occurs with psychiatric and gastrointestinal disorders. A recent genome-wide association study (GWAS) identified several genetic risk variants for IBS. However, most of the heritability remains unidentified, and the genetic overlap with psy...

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Egile Nagusiak:	Markos Tesfaye, Piotr Jaholkowski, Guy F. L. Hindley, Alexey A. Shadrin, Zillur Rahman, Shahram Bahrami, Aihua Lin, Børge Holen, Nadine Parker, Weiqiu Cheng, Linn Rødevand, Oleksandr Frei, Srdjan Djurovic, Anders M. Dale, Olav B. Smeland, Kevin S. O’Connell, Ole A. Andreassen
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2023-08-01
Saila:	Genome Medicine
Gaiak:	Irritable bowel syndrome Genetic overlap Psychiatric disorder Gut-brain axis
Sarrera elektronikoa:	https://doi.org/10.1186/s13073-023-01212-4
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