Codice QR

Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia

CDC42 controls intestinal epithelial (IEC) stem cell (IESC) division. How aberrant CDC42 initiates intestinal inflammation or neoplasia is unclear. We utilized models of inflammatory bowel diseases (IBD), colorectal cancer, aging, and IESC injury to determine the loss of intestinal Cdc42 upon inflam...

Descrizione completa

Salvato in:
Autori principali: Dongsheng Zhang, Wenjuan Tang, Haitao Niu, William Tse, Hai-Bin Ruan, Helmut Dolznig, Thomas Knösel, Friedrich Karl-Heinz, Madeleine Themanns, Jiang Wang, Mingquan Song, Lee Denson, Lukas Kenner, Richard Moriggl, Yi Zheng, Xiaonan Han
Natura: Artigo
Lingua:Inglês
Pubblicazione: KeAi Communications Co., Ltd. 2024-01-01
Serie:Genes and Diseases
Soggetti:
Cell division cycle 42 (CDC42)
Colitis
Colorectal cancer (CRC)
Inflammatory bowel diseases (IBD)
Intestinal epithelial cell (IEC)
Intestinal epithelial stem cell (IESC)
Accesso online:http://www.sciencedirect.com/science/article/pii/S2352304222003300
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi