Macrophage mitophagy-related genes predict prognosis and therapeutic response in lung adenocarcinoma

Abstract Mitochondrial autophagy (mitophagy) in macrophages is crucial yet poorly understood within the lung adenocarcinoma (LUAD) tumor microenvironment. This study aimed to identify key macrophage mitophagy-related genes and develop a robust prognostic model for LUAD patients. By integrating singl...

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Autori principali:	TianRong Yang, Qin Liu, Wei Li, Bin Pan, JingFei Jiang, HongMei Tan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-11-01
Serie:	Scientific Reports
Soggetti:	Lung adenocarcinoma Mitophagy Macrophages Single-cell transcriptomics Machine learning Drug sensitivity
Accesso online:	https://doi.org/10.1038/s41598-025-24769-z
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