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Macrophage mitophagy-related genes predict prognosis and therapeutic response in lung adenocarcinoma

Abstract Mitochondrial autophagy (mitophagy) in macrophages is crucial yet poorly understood within the lung adenocarcinoma (LUAD) tumor microenvironment. This study aimed to identify key macrophage mitophagy-related genes and develop a robust prognostic model for LUAD patients. By integrating singl...

Deskribapen osoa

Gorde:
Egile Nagusiak: TianRong Yang, Qin Liu, Wei Li, Bin Pan, JingFei Jiang, HongMei Tan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-11-01
Saila:Scientific Reports
Gaiak:
Lung adenocarcinoma
Mitophagy
Macrophages
Single-cell transcriptomics
Machine learning
Drug sensitivity
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-24769-z
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