Salmonella Typhimurium derived OMV nanoparticle displaying mixed heterologous O-antigens confers immunogenicity and protection against STEC infections in mice

Abstract Shiga toxin-producing Escherichia coli (STEC) is one of the major pathogens responsible for severe foodborne infections, and the common serotypes include E. coli O157, O26, O45, O103, O111, O121, and O145. Vaccination has the potential to prevent STEC infections, but no licensed vaccines ar...

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主要な著者:	Xiaoping Bian, Yaolin Chen, Wenjin Zhang, Xinyu Liu, Meihong Lei, Haoxiang Yuan, Mengru Li, Qing Liu, Qingke Kong
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-01-01
シリーズ:	Microbial Cell Factories
主題:	OMV STEC O-antigen Genetically engineered Salmonella
オンライン･アクセス:	https://doi.org/10.1186/s12934-024-02640-6
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