Salmonella Typhimurium derived OMV nanoparticle displaying mixed heterologous O-antigens confers immunogenicity and protection against STEC infections in mice

Abstract Shiga toxin-producing Escherichia coli (STEC) is one of the major pathogens responsible for severe foodborne infections, and the common serotypes include E. coli O157, O26, O45, O103, O111, O121, and O145. Vaccination has the potential to prevent STEC infections, but no licensed vaccines ar...

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Autors principals:	Xiaoping Bian, Yaolin Chen, Wenjin Zhang, Xinyu Liu, Meihong Lei, Haoxiang Yuan, Mengru Li, Qing Liu, Qingke Kong
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-01-01
Col·lecció:	Microbial Cell Factories
Matèries:	OMV STEC O-antigen Genetically engineered Salmonella
Accés en línia:	https://doi.org/10.1186/s12934-024-02640-6
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