Salmonella Typhimurium derived OMV nanoparticle displaying mixed heterologous O-antigens confers immunogenicity and protection against STEC infections in mice

Abstract Shiga toxin-producing Escherichia coli (STEC) is one of the major pathogens responsible for severe foodborne infections, and the common serotypes include E. coli O157, O26, O45, O103, O111, O121, and O145. Vaccination has the potential to prevent STEC infections, but no licensed vaccines ar...

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Hlavní autoři:	Xiaoping Bian, Yaolin Chen, Wenjin Zhang, Xinyu Liu, Meihong Lei, Haoxiang Yuan, Mengru Li, Qing Liu, Qingke Kong
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-01-01
Edice:	Microbial Cell Factories
Témata:	OMV STEC O-antigen Genetically engineered Salmonella
On-line přístup:	https://doi.org/10.1186/s12934-024-02640-6
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