The ESCRT-III molecules regulate the apical targeting of bile salt export pump
Abstract Background The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow. Defects in BSEP function and canalicular expression could lead to a spectrum of cholestatic liver diseases. One prominent manifestation of BSEP-associa...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2021-03-01
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| Edice: | Journal of Biomedical Science |
| Témata: | |
| On-line přístup: | https://doi.org/10.1186/s12929-020-00706-2 |
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