Cu-catalyzed asymmetric addition of alcohols to β,γ-alkynyl-α-imino esters for the construction of linear chiral N,O-ketals
N,O-acetals are part of many synthetic intermediates and important skeletons of numerous natural products and pharmaceutical drugs. Here the authors show a Cu-catalyzed asymmetric addition of alcohols to β,γ-alkynyl-α-imino esters, providing the corresponding linear chiral N,O-ketals with up to 96%...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2022-01-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-022-28002-7 |
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