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Cu-catalyzed asymmetric addition of alcohols to β,γ-alkynyl-α-imino esters for the construction of linear chiral N,O-ketals

N,O-acetals are part of many synthetic intermediates and important skeletons of numerous natural products and pharmaceutical drugs. Here the authors show a Cu-catalyzed asymmetric addition of alcohols to β,γ-alkynyl-α-imino esters, providing the corresponding linear chiral N,O-ketals with up to 96%...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cheng Sheng, Zheng Ling, Yicong Luo, Wanbin Zhang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2022-01-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/s41467-022-28002-7
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