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Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1

Effective cancer chemotherapy treatment requires both therapy delivery and retention by malignant cells. Cancer cell overexpression of the multidrug transmembrane transporter gene ABCB1 (MDR1, multi-drug resistance protein 1) thwarts therapy retention, leading to a drug-resistant phenotype. We explo...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Jasmine A. McQuerry, Jinfeng Chen, Jeffrey T. Chang, Andrea H. Bild
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Elsevier 2021-10-01
Sraith:Translational Oncology
Ábhair:
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S193652332100173X
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