Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1

Effective cancer chemotherapy treatment requires both therapy delivery and retention by malignant cells. Cancer cell overexpression of the multidrug transmembrane transporter gene ABCB1 (MDR1, multi-drug resistance protein 1) thwarts therapy retention, leading to a drug-resistant phenotype. We explo...

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Principais autores:	Jasmine A. McQuerry, Jinfeng Chen, Jeffrey T. Chang, Andrea H. Bild
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2021-10-01
Serija:	Translational Oncology
Teme:	ABCB1 Breast cancer Drug resistance Cyclooxygenase Histone deacetylase inhibitor
Online dostop:	http://www.sciencedirect.com/science/article/pii/S193652332100173X
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