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A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway

Abstract Background Long noncoding RNAs (lncRNAs) are recently found to be critical regulators of the epigenome. However, our knowledge of their role in osteoarthritis (OA) development is limited. This study investigates the mechanism by which HOTAIR, a key lncRNA with elevated expression in OA, aff...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yang Yang, Dan Xing, Yawei Wang, Haobo Jia, Bing Li, Jiao Jiao Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2020-07-01
Rangatū:BMC Molecular and Cell Biology
Ngā marau:
Urunga tuihono:http://link.springer.com/article/10.1186/s12860-020-00299-6
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