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LncRNA HOTAIR facilitates high glucose-induced mesangial cell proliferation, fibrosis and oxidative stress in diabetic nephropathy via regulating miR-147a/WNT2B axis

Abstract Background Long non-coding RNAs (lncRNAs) have been shown to be involved in the regulation of many disease progression. However, the role of lncRNA HOX transcript antisense RNA (HOTAIR) in diabetic nephropathy (DN) remains unclear. Methods High glucose (HG)-induced human mesangial cells (HM...

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Autors principals: Xin Wang, Wei Wang, Weizhong HuangFu, Zhonghua Liu, Feng Zhao
Format: Artigo
Idioma:Inglês
Publicat: BMC 2022-02-01
Col·lecció:Diabetology & Metabolic Syndrome
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Accés en línia:https://doi.org/10.1186/s13098-022-00802-3
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