Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model

Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD₅₀ of ~1 ng/kg. Equine antitoxin has a half-life in circulation of less than 1 day and is limited to a treatment rather than a prevention indication. The development of monoclonal antibodies (mAbs) may...

Descripción completa

Detalles Bibliográficos

Autores principales:	Milan T. Tomic, Yero Espinoza, Zachary Martinez, Khanh Pham, Ronald R. Cobb, Doris M. Snow, Christopher G. Earnhart, Traci Pals, Emily S. Syar, Nancy Niemuth, Dean J. Kobs, Shauna Farr-Jones, James D. Marks
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2019-04-01
Colección:	Toxins
Materias:	botulinum neurotoxin aerosol monoclonal antibody guinea pig inhalation model oligoclonal antibody inhalational botulism botulism
Acceso en línea:	https://www.mdpi.com/2072-6651/11/4/208
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!