Cytochrome b5 reductase is the component from neuronal synaptic plasma membrane vesicles that generates superoxide anion upon stimulation by cytochrome c

In this work, we measured the effect of cytochrome c on the NADH-dependent superoxide anion production by synaptic plasma membrane vesicles from rat brain. In these membranes, the cytochrome c stimulated NADH-dependent superoxide anion production was inhibited by antibodies against cytochrome b5 red...

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Autori principali:	Alejandro K. Samhan-Arias, Sofia Fortalezas, Cristina M. Cordas, Isabel Moura, José J.G. Moura, Carlos Gutierrez-Merino
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2018-05-01
Serie:	Redox Biology
Soggetti:	Cb5R, Cytochrome b5 reductase DTPA, Diethylenetriaminepentaacetic acid DHE, Dihydroethidium E+, Ethidium FAD, Flavin adenine dinucleotide NADH, Reduced nicotinamide adenine dinucleotide NBT, Nitroblue tetrazolium nitroblue tetrazolium SPMV, Synaptic plasma membrane vesicles TB, Terrific Broth terrific Broth SOD, Superoxide dismutase XA, Xanthine xanthine XO, Xanthine oxidase
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2213231717308005
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