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Effective holistic characterization of small molecule effects using heterogeneous biological networks

The two most common reasons for attrition in therapeutic clinical trials are efficacy and safety. We integrated heterogeneous data to create a human interactome network to comprehensively describe drug behavior in biological systems, with the goal of accurate therapeutic candidate generation. The Co...

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Detaylı Bibliyografya
Asıl Yazarlar: William Mangione, Zackary Falls, Ram Samudrala
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2023-04-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fphar.2023.1113007/full
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