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Synthesis of Berberine and Canagliflozin Chimera and Investigation into New Antibacterial Activity and Mechanisms

Berberine is an isoquinoline alkaloid isolated from Chinese herbal medicines such as Coptis chinensis. It has many pharmacological actions, such as antibacterial, hypoglycemic, anti-inflammatory, and so on. However, due to the low lipophilicity of berberine, it is difficult to penetrate the bacteria...

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Hlavní autoři: Wenhui Hao, Shiying Che, Jinsheng Li, Jingyi Luo, Wanqiu Zhang, Yang Chen, Zijian Zhao, Hao Wei, Weidong Xie
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-05-01
Edice:Molecules
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On-line přístup:https://www.mdpi.com/1420-3049/27/9/2948
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