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Voxelotor (GBT440) in pediatric sickle cell disease: A review

Sickle cell disease (SCD) was first described in 1910 in African Americans, and the mutant hemoglobin S (HbS) was identified by electrophoresis in 1948. Sickle cell disease is the first genetic disease to be molecularly defined - a single point mutation in the β-globin gene (GAG→GTG) results in subs...

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Detalhes bibliográficos
Principais autores: Sri Lakshmi Jamalapur, Alexander K. Glaros, Yaddanapudi Ravindranath
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-12-01
coleção:Pediatric Hematology Oncology Journal
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2468124524000615
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