Hypoxic microenvironment in cancer: role in metabolic reprogramming

Hypoxia, a defining hallmark of solid tumors, arises from structurally and functionally abnormal vasculature, rapid cellular proliferation, and impaired perfusion, resulting in chronic and cycling oxygen deprivation within the tumor massThe hypoxic tumor microenvironment orchestrates extensive molec...

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Bibliografiske detaljer

Principais autores:	Niti Sureka, Rashi Maheshwari, Amit Agravat, Shweta Singhal, Shamsuz Zaman, Bhavika Rishi, Fouzia Siraj, Sufian Zaheer, Aroonima Misra
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2026-03-01
Serier:	Frontiers in Oncology
Fag:	hypoxia hypoxia-inducible factors (HIFs) immune evasion metabolic reprogramming mitochondrial metabolism tumor microenvironment (TME)
Online adgang:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1771365/full
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