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Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology

Abstract Background Migraine is a prevalent neurological disorder affecting 14.1% of the global population. Despite advances in genetic research, further investigation is needed to identify therapeutic targets and better understand its mechanisms. In this study, we aimed to identify drug targets and...

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Detaylı Bibliyografya
Asıl Yazarlar: Jiafei Lou, Miaoqian Tu, Maosheng Xu, Zhijian Cao, Wenwen Song
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-11-01
Seri Bilgileri:The Journal of Headache and Pain
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Online Erişim:https://doi.org/10.1186/s10194-024-01922-z
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