Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions

Summary: The choroid plexus is a major site for cerebrospinal fluid (CSF) production, characterized by a multiciliated epithelial monolayer that regulates CSF production. We demonstrate that defective choroid plexus ciliogenesis or intraflagellar transport yields neonatal hydrocephalus, at least in...

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Detalhes bibliográficos

Principais autores:	Suifang Mao, Rui Song, Shibo Jin, Song Pang, Aleksandra Jovanovic, Adam Zimmerman, Peng Li, Xinying Wu, Michael F. Wendland, Kerry Lin, Wei-Chi Chen, Semil P. Choksi, Gang Chen, Michael J. Holtzman, Jeremy F. Reiter, Ying Wan, Zhenyu Xuan, Yang K. Xiang, C. Shan Xu, Srigokul Upadhyayula, Harald F. Hess, Lin He
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-03-01
coleção:	Cell Reports
Assuntos:	CP: Cell biology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124725001548
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