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Affimer reagents enable targeted delivery of therapeutic agents and RNA via virus-like particles

Summary: Monoclonal antibodies have revolutionized therapies, but non-immunoglobulin scaffolds are becoming compelling alternatives owing to their adaptability. Their ability to be labeled with imaging or cytotoxic compounds and to create multimeric proteins is an attractive strategy for therapeutic...

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Bibliografiske detaljer
Principais autores: Sophie E. Roberts, Heather L. Martin, Danah Al-Qallaf, Anna A. Tang, Christian Tiede, Thembaninkosi G. Gaule, Albor Dobon-Alonso, Ross Overman, Sachin Shah, Hadrien Peyret, Keith Saunders, Robin Bon, Iain W. Manfield, Sandra M. Bell, George P. Lomonossoff, Valerie Speirs, Darren C. Tomlinson
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-08-01
Serier:iScience
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004224016869
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