Affimers targeting proteins in the cardiomyocyte Z-disc: Novel tools that improve imaging of heart tissue

Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human heart is important in understanding how the heart becomes less effective at contraction. Here we isolated and characterised Affimers (small non...

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Autori principali:	Francine Parker, Anna A. S. Tang, Brendan Rogers, Glenn Carrington, Cris dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-02-01
Serie:	Frontiers in Cardiovascular Medicine
Soggetti:	Dilated Cardiomyopathy Affimer Z-disc intercalated disc fluorescence microscopy cardiac actinin
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1094563/full
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