Multi-modal contrastive drug synergy prediction model guided by single modality

Abstract Compared to monotherapy, drug combinations exhibit stronger efficacy, fewer side effects, and lower drug resistance in cancer treatment. However, traditional wet-lab methods for screening synergistic drug combinations are both costly and inefficient. Lately, the development of various drug...

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Podrobná bibliografie

Hlavní autoři:	Tong Luo, Zheng Zhang, Xian-gan Chen, Zhi Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-09-01
Edice:	Journal of Cheminformatics
Témata:	Drug synergy prediction Multi-modal contrastive learning Single modality guidance Heterogeneous graph network
On-line přístup:	https://doi.org/10.1186/s13321-025-01087-0
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