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Multi-modal contrastive drug synergy prediction model guided by single modality

Abstract Compared to monotherapy, drug combinations exhibit stronger efficacy, fewer side effects, and lower drug resistance in cancer treatment. However, traditional wet-lab methods for screening synergistic drug combinations are both costly and inefficient. Lately, the development of various drug...

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Bibliographic Details
Main Authors: Tong Luo, Zheng Zhang, Xian-gan Chen, Zhi Li
Format: Artigo
Language:Inglês
Published: BMC 2025-09-01
Series:Journal of Cheminformatics
Subjects:
Online Access:https://doi.org/10.1186/s13321-025-01087-0
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