Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder
Phosphorylation events that occur in response to the second messenger cAMP are controlled spatially and temporally by protein kinase A (PKA) interacting with A-kinase anchoring proteins (AKAPs). Recent advances in understanding the structural basis for this interaction have reinforced the hypothesis...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2015-07-01
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| Serier: | Frontiers in Pharmacology |
| Fag: | |
| Online adgang: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00158/full |
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