Autophagic Schwann cells promote perineural invasion mediated by the NGF/ATG7 paracrine pathway in pancreatic cancer

Abstract Background Perineural invasion (PNI) and autophagy are two common features in the tumor microenvironment of pancreatic cancer (PanCa) and have a negative effect on prognosis. Potential mediator cells and the molecular mechanism underlying their relationships need to be fully elucidated. Met...

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Autors principals:	Wunai Zhang, Rui He, Wenbin Yang, Yan Zhang, Qinggong Yuan, Jixin Wang, Yang Liu, Shuo Chen, Simei Zhang, Weifan Zhang, Zeen Zhu, Jing Zhang, Zheng Wang, Junhui Li
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-02-01
Col·lecció:	Journal of Experimental & Clinical Cancer Research
Matèries:	Pancreatic cancer Schwann cells Autophagy NGF Perineural invasion
Accés en línia:	https://doi.org/10.1186/s13046-021-02198-w
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