Effects of interleukin-17A on osteogenic differentiation of isolated human mesenchymal stem cells

OBJECTIVES: Rheumatoid arthritis (RA) is characterized by defective bone repair and excessive destruction, and ankylosing spondylitis (AS) by increased ectopic bone formation with syndesmophytes. Since TNF-α and IL-17A are involved in both diseases, this study investigated their effects on the osteo...

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Detalhes bibliográficos

Principais autores:	Bilal eOsta, Fabien eLavocat, Assia eEljaafari, Pierre eMiossec
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-09-01
coleção:	Frontiers in Immunology
Assuntos:	Rheumatoid arthritis mesenchymal stem cell IL-17A TNF-α ankylosing spondylitis.
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00425/full
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