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Interleukin-25 Produced by Synoviocytes Has Anti-inflammatory Effects by Acting As a Receptor Antagonist for Interleukin-17A Function

The production and function of cytokines are highly regulated. One mechanism is the balance between pro- and anti-inflammatory cytokines. As interleukin (IL)-17A and IL-25 share the IL-17RA receptor chain, we hypothesize that IL-25 acts as an IL-17A receptor antagonist and limits its pro-inflammator...

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Autors principals: Fabien Lavocat, Ndiémé Ndongo-Thiam, Pierre Miossec
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017-05-01
Col·lecció:Frontiers in Immunology
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Accés en línia:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00647/full
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