Glucocorticoid repression of inflammatory gene expression shows differential responsiveness by transactivation- and transrepression-dependent mechanisms.

Binding of glucocorticoid to the glucocorticoid receptor (GR/NR3C1) may repress inflammatory gene transcription via direct, protein synthesis-independent processes (transrepression), or by activating transcription (transactivation) of multiple anti-inflammatory/repressive factors. Using human pulmon...

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Библиографические подробности

Главные авторы:	Elizabeth M King, Joanna E Chivers, Christopher F Rider, Anne Minnich, Mark A Giembycz, Robert Newton
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2013-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC3545719?pdf=render
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